Description

4-Bromo-L-Phenylalanine is a halogenated derivative of the essential amino acid L-phenylalanine, serving as a crucial chiral building block in organic synthesis. This compound matters for its role in introducing the bromophenyl moiety, a key structural feature for modulating biological activity and physicochemical properties in target molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, enzyme inhibitors, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and neurology.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a brominated aromatic side chain, enabling further functionalization via cross-coupling reactions.
• Proteomics & Biochemistry Research: Serves as a precursor for labeled amino acids or as a tool compound for studying enzyme mechanisms and protein interactions.
• Chemical Biology Probes: Foundation for creating photoaffinity labels, enzyme inhibitors, and other molecular probes due to the reactive bromine handle.
• Material Science: Potential monomer or precursor for specialized polymers and advanced organic materials requiring halogenated aromatic components.

Basic Information

Product Name	4-Bromo-L-Phenylalanine
CAS No.	24250-84-8
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	(S)-2-Amino-3-(4-bromophenyl)propanoic acid; L-4-Bromophenylalanine; p-Bromo-L-phenylalanine; (S)-4-Bromophenylalanine; H-4-Br-Phe-OH; Fmoc-4-Bromo-L-phenylalanine (precursor form); BOC-4-Bromo-L-phenylalanine (precursor form); 4-Bromo-DL-phenylalanine (racemic mixture)
EINECS	Contact for details

Quality Control

Our 4-Bromo-L-Phenylalanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, specific rotation, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Specific Rotation	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.