Description

H-Leu-Leu-Val-Phe-Oh CAS NO 24205-68-3 is a synthetic tetrapeptide sequence composed of leucine, valine, and phenylalanine residues, serving as a crucial building block in advanced peptide synthesis and biochemical research. This compound is valued for its role in studying protein folding, enzyme-substrate interactions, and as a precursor for more complex bioactive peptides. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Research & Development: Used as an intermediate in the synthesis of novel peptide-based drug candidates and for structure-activity relationship (SAR) studies.
• Biochemical Reagent: Serves as a substrate or inhibitor in enzymatic assays to study protease activity and specificity.
• Proteomics & Peptide Mapping: Employed as a reference standard in mass spectrometry for peptide identification and quantification.
• Academic Research: A key tool for investigating peptide conformation, aggregation behavior, and molecular recognition processes in university laboratories.
• Cosmeceutical Development: Explored as a potential active ingredient or structural motif in anti-aging and skin-repair formulations.
• Chemical Biology Probes: Utilized in the design and synthesis of labeled peptides for cellular imaging and target engagement studies.

Basic Information

Item	Detail
Product Name	H-Leu-Leu-Val-Phe-Oh
CAS No.	24205-68-3
Molecular Formula	C26H42N4O5
Molecular Weight	490.64 g/mol
Synonyms	L-Leucyl-L-leucyl-L-valyl-L-phenylalanine; Leu-Leu-Val-Phe; LLVF; H-LLVF-OH; Tetrapeptide LLVF; N-(N-(N-L-Leucyl-L-leucyl)-L-valyl)-L-phenylalanine; (S)-2-((S)-2-((S)-2-((S)-2-Amino-4-methylpentanamido)-4-methylpentanamido)-3-methylbutanamido)-3-phenylpropanoic acid
EINECS	Contact for details

Quality Control

Our H-Leu-Leu-Val-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral purity analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.