Description

n-[(Benzyloxy)Carbonyl]-S-Benzyl-L-Cysteine Hydrazide is a protected cysteine derivative of significant importance in peptide synthesis and pharmaceutical research. This compound serves as a critical building block for the controlled introduction of cysteine residues, enabling the study of disulfide bond formation and protein structure. It is primarily needed by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in advanced peptide chemistry and the production of bioactive molecules.

Application

• Peptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of cysteine-containing peptides.
• Pharmaceutical Intermediates: Used in the research and development of novel therapeutic peptides and protein-based drugs.
• Bioconjugation Chemistry: Acts as a precursor for creating linkers or functional handles for protein labeling and antibody-drug conjugates (ADCs).
• Chemical Biology Research: Employed in studies investigating thiol reactivity, redox processes, and enzyme mechanisms.
• Protecting Group Strategy: The Z (Cbz) and S-benzyl groups offer orthogonal protection, allowing for selective deprotection in complex multi-step syntheses.
• Reference Standard: Serves as a high-purity analytical standard for quality control in peptide manufacturing.

Basic Information

Item	Detail
Product Name	n-[(Benzyloxy)Carbonyl]-S-Benzyl-L-Cysteine Hydrazide
CAS No.	24164-46-3
Molecular Formula	C18H21N3O3S
Molecular Weight	359.44 g/mol
Synonyms	Z-Cys(Bzl)-NHNH2; Cbz-Cys(Bzl)-Hydrazide; N-Carbobenzoxy-S-benzyl-L-cysteine hydrazide; L-Cysteine, N-[(phenylmethoxy)carbonyl]-S-(phenylmethyl)-, hydrazide; (2R)-2-[(Benzyloxy)carbonylamino]-3-(phenylmethylsulfanyl)propanehydrazide; Cbz-S-benzyl-L-cysteine hydrazide; Z-S-Benzyl-L-cysteine hydrazide
EINECS	Contact for details

Quality Control

Our n-[(Benzyloxy)Carbonyl]-S-Benzyl-L-Cysteine Hydrazide is manufactured under strict quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]D20: Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.