Description

Argipressin, Asu(1,6)- is a synthetic analogue of the neurohypophysial hormone arginine vasopressin, characterized by the substitution of the 1,6-disulfide bridge with a 1,6-ethylene bridge (Asu). This modification confers distinct pharmacological properties, making it a valuable research tool and a key intermediate in peptide synthesis. It is primarily utilized in advanced biochemical research, pharmaceutical development, and the production of specialized peptide-based compounds. This product is essential for researchers and manufacturers in the fields of endocrinology, neurobiology, and peptide drug discovery.

Application

• Biochemical Research: Used as a reference standard and active compound in studies investigating vasopressin receptor (V1a, V2) binding, signaling pathways, and physiological effects.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of novel vasopressin analogues with potential therapeutic applications.
• In Vitro Diagnostics: Employed in the development and calibration of immunoassays (e.g., ELISA, RIA) for vasopressin-related research.
• Neuroscience Studies: Applied in research models to study the role of vasopressin in memory, social behavior, stress response, and central autonomic regulation.
• Peptide Chemistry: A model compound for studying structure-activity relationships (SAR) in modified cyclic peptides.
• Quality Control: Used as an analytical reference standard in pharmaceutical quality control laboratories to ensure the purity and identity of related products.

Basic Information

Product Name	Argipressin, Asu(1,6)-
CAS No.	24057-83-8
Molecular Formula	C46H65N13O12S2
Molecular Weight	1032.2 g/mol
Synonyms	[1-β-Mercaptopropionic acid, 6-D-arginine]vasopressin; [1-Deamino, 6-D-Arg]vasopressin; dDAVP analogue; Desmopressin analogue; 1-Deamino-8-D-arginine vasopressin (disulfide bridge modified); AVP analogue; Cyclo(1-6)[Cys1,D-Arg8]vasopressin (Asu1,6); (1-β-Mercaptopropionic acid, 8-D-arginine)vasopressin
EINECS	Contact for details

Quality Control

Our Argipressin, Asu(1,6)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and documentation. Certificates of Analysis (COA) detailing all test results are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular ion peak matches theoretical mass
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.