Description

2-Hydroxy-D-Phenylalanine is a non-proteinogenic amino acid derivative of phenylalanine, characterized by a hydroxyl group at the ortho position of the aromatic ring. This specific D-enantiomer is a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel drug candidates, particularly in neuroscience and metabolic disorders.
• Biochemical Research: Used as a precursor or standard in enzymatic studies, metabolic pathway analysis, and studies of amino acid metabolism.
• Peptide Synthesis: Serves as a specialized, non-natural amino acid residue in the synthesis of modified peptides with enhanced stability or biological activity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective chemical reactions to induce desired chirality in target molecules.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control testing of related compounds.

Basic Information

Product Name	2-Hydroxy-D-Phenylalanine
CAS No.	24008-77-3
Molecular Formula	C9H11NO3
Molecular Weight	181.19 g/mol
Synonyms	D-2-Hydroxyphenylalanine; (R)-2-Amino-3-(2-hydroxyphenyl)propanoic acid; D-o-Tyrosine; D-ortho-Tyrosine; (R)-2-Hydroxyphenylalanine; H-D-o-Tyr-OH; 2-Hydroxy-D-phenylglycine (related); D-2-HPA
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-D-Phenylalanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.