Description

2-Mercapto-4-Hydroxy-5-Cyanopyrimidine is a versatile heterocyclic building block characterized by its reactive thiol, hydroxyl, and nitrile functional groups. This compound matters as a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it enables the construction of pyrimidine-based active ingredients. It is essential for research chemists and process development teams in fine chemical, pharmaceutical, and advanced material industries seeking to develop novel compounds with specific biological or material properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antiviral, anticancer, and other biologically active pyrimidine derivatives.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Building Block: Employed in organic synthesis for constructing complex heterocyclic scaffolds in research and development.
• Material Science Research: Investigated as a monomer or ligand for the development of specialized polymers or coordination complexes.
• Bioconjugation Chemistry: The thiol group can be utilized for coupling reactions in the modification of proteins or other biomolecules.

Basic Information

Product Name	2-Mercapto-4-Hydroxy-5-Cyanopyrimidine
CAS No.	23945-49-5
Molecular Formula	C5H3N3OS
Molecular Weight	153.16 g/mol
Synonyms	5-Cyano-2-mercapto-4-hydroxypyrimidine; 4-Hydroxy-2-mercapto-5-cyanopyrimidine; 2-Thio-4-hydroxy-5-cyanopyrimidine; 2-Mercapto-4-hydroxy-5-pyrimidinecarbonitrile; 5-Cyano-2-thiouracil; 23945-49-5; 2-Thiobarbituric acid nitrile
EINECS	Contact for details

Quality Control

Our 2-Mercapto-4-Hydroxy-5-Cyanopyrimidine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.