Description

α-n-Formyl-(ε-n-1-Deoxy-1-Fructosyl)-L-Lysine is a chemically defined advanced glycation end-product (AGE) precursor and a key reference standard in biochemical research. This compound is critical for studying the Maillard reaction pathway, protein glycation, and the mechanisms underlying diabetic complications and aging. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in metabolic disease research, diagnostic assay development, and drug discovery programs.

Application

• Biochemical Research Standard: Serves as a high-purity reference compound for studying non-enzymatic glycation and the formation of advanced glycation end-products (AGEs).
• Diagnostic Development: Used as a calibrant or antigen in the development and validation of immunoassays and ELISA kits for detecting glycated proteins and AGEs.
• Metabolic Disease Studies: Essential for in vitro and in vivo research models investigating the pathophysiological role of AGEs in diabetes, aging, and related complications.
• Pharmaceutical Screening: Employed as a target or inhibitor in high-throughput screening assays to discover potential therapeutic agents against AGE-mediated damage.
• Food Science Research: Applied in studies analyzing the Maillard reaction in food processing, nutrition, and the formation of dietary AGEs.

Basic Information

Product Name	α-n-Formyl-(ε-n-1-Deoxy-1-Fructosyl)-L-Lysine
CAS No.	23931-59-1
Molecular Formula	C14H26N2O8
Molecular Weight	350.37 g/mol
Synonyms	Nα-Formyl-Nε-(1-deoxy-D-fructos-1-yl)-L-lysine; Nα-Formyl-fructosyl-lysine; FFI; Formylfructosyllysine; N-Formyl-N-(1-deoxyfructosyl)lysine; Amadori product of Nα-Formyl-L-lysine; AGE Precursor; 1-Deoxy-1-(N6-formyl-L-lysino)-D-fructose
EINECS	Contact for details

Quality Control

Our α-n-Formyl-(ε-n-1-Deoxy-1-Fructosyl)-L-Lysine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and specific tests for related substances. A detailed Certificate of Analysis (COA) documenting identity, purity, and assay is provided with every shipment to ensure it meets the exacting standards required for research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.