Description

3-(2-Fluorophenyl)-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One is a specialized heterocyclic organic compound featuring a quinazolinone core substituted with a fluorophenyl group and a thioxo moiety. This unique molecular structure makes it a valuable key intermediate and building block for advanced chemical synthesis. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used as a building block for developing new pesticides and herbicides, leveraging its fluorinated aromatic structure.
• Material Science: Investigated for the creation of advanced organic materials, including ligands for catalysis and components for organic electronics.
• Chemical Biology: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Academic & Industrial R&D: A versatile scaffold for medicinal chemistry programs and exploratory synthetic chemistry in both university and corporate research settings.

Basic Information

Item	Details
Product Name	3-(2-Fluorophenyl)-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One
CAS No.	23892-21-9
Molecular Formula	C₁₄H₉FN₂OS
Molecular Weight	272.30 g/mol
Synonyms	3-(2-Fluorophenyl)-2-thioxo-1,2,3,4-tetrahydroquinazolin-4-one; 2-Thioxo-3-(o-fluorophenyl)-1,2,3,4-tetrahydro-4-quinazolinone; 3-(2-Fluorophenyl)-2-mercapto-3,4-dihydro-4-quinazolinone; 23892-21-9; Quinazolin-4(1H)-one, 3-(2-fluorophenyl)-2,3-dihydro-2-thioxo-; 3-(2-Fluorophenyl)-2-thioxo-1,2,3,4-tetrahydroquinazolin-4-one
EINECS	Contact for details

Quality Control

Our production of 3-(2-Fluorophenyl)-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.