Description

H-Arg-Pro-Pro-Gly-Phe-Oh Trifluoroacetate Salt is a synthetic peptide derivative, specifically a pentapeptide amide, supplied as a trifluoroacetate salt to enhance stability and solubility. This compound is a critical intermediate in pharmaceutical research and development, particularly for studying protease inhibition and cardiovascular function. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require high-purity peptide building blocks for drug discovery and biochemical studies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study protease activity and kinetics.
• Cardiovascular Research: Investigated for its potential role in modulating blood pressure and vascular function due to its structural similarity to bioactive peptides.
• Peptide Library Synthesis: A valuable building block for constructing combinatorial peptide libraries for high-throughput screening.
• Reference Standard: Employed as a certified reference material (CRM) for analytical method development and quality control in peptide manufacturing.
• Academic Research: Utilized in university and institutional labs for fundamental studies in peptide chemistry and molecular biology.

Basic Information

Product Name	H-Arg-Pro-Pro-Gly-Phe-Oh Trifluoroacetate Salt
CAS No.	23815-89-6
Molecular Formula	C30H45N9O7 • xC2HF3O2
Molecular Weight	643.74 g/mol (free base)
Synonyms	Arg-Pro-Pro-Gly-Phe-OH TFA salt; RPPGF TFA; H-Arg-Pro-Pro-Gly-Phe TFA; Bradykinin potentiator peptide fragment; Pentapeptide RPPGF TFA salt; ARG-PRO-PRO-GLY-PHE TFA; H-Arg-Pro-Pro-Gly-Phe Amide TFA Salt; 23815-89-6 (TFA salt)
EINECS	Contact for details

Quality Control

Our H-Arg-Pro-Pro-Gly-Phe-Oh Trifluoroacetate Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For extended storage under inert atmosphere, contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Water Content (KF)	≤ 5.0%
Residual TFA (NMR/HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.