Description

Bradykinin (1-6) is a bioactive hexapeptide fragment derived from the endogenous vasoactive peptide bradykinin. This compound is a critical research tool for investigating the structure-activity relationships of kinins and their role in inflammatory and cardiovascular pathways. It is primarily utilized by pharmaceutical researchers, biochemical laboratories, and academic institutions focused on peptide science, drug discovery, and physiological studies.

Application

• Biochemical Research: Used as a reference standard and substrate in enzymatic studies to understand bradykinin metabolism and kininase activity.
• Pharmacological Studies: Serves as a key intermediate for investigating the minimal active sequence of bradykinin and developing receptor antagonists or agonists.
• Inflammation & Pain Research: Applied in vitro and in vivo models to study the role of bradykinin fragments in mediating inflammatory responses and pain signaling.
• Peptide Synthesis: Acts as a building block or a synthetic intermediate for the preparation of longer, modified bradykinin analogs and conjugates.
• Diagnostic Development: Potential use in the development of immunoassays and diagnostic kits targeting the kinin system.
• Academic & Educational Use: Employed in university laboratories for teaching advanced concepts in peptide chemistry and neuropharmacology.

Basic Information

Product Name	Bradykinin (1-6)
CAS No.	23815-88-5
Molecular Formula	C30H47N9O9
Molecular Weight	677.76 g/mol
Synonyms	Arg-Pro-Pro-Gly-Phe-Ser; Bradykinin 1-6; BK (1-6); H-Arg-Pro-Pro-Gly-Phe-Ser-OH; RPPGFS; Des-Phe8-Arg9-Bradykinin; Bradykinin fragment 1-6
EINECS	Contact for details

Quality Control

Our Bradykinin (1-6) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous quality testing protocols, and specifications can be aligned with research-grade or higher standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.