Description

H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Oh Acetate Salt is a high-purity synthetic peptide acetate salt, specifically the C-terminal heptapeptide fragment of the neuropeptide Bradykinin. This compound is of significant interest in biochemical and pharmacological research due to its role as a key metabolite and a potential modulator of bradykinin receptor activity. It serves as a critical reference standard and building block for researchers and manufacturers in the pharmaceutical and life science sectors, enabling studies on inflammation, pain pathways, and cardiovascular function.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutics targeting the kallikrein-kinin system.
• Biochemical Assays: Essential for in vitro and in vivo studies to investigate bradykinin metabolism, receptor binding affinity, and signal transduction mechanisms.
• Peptide Synthesis: Serves as a key fragment for the solid-phase or solution-phase synthesis of longer, modified bradykinin-related peptides for structure-activity relationship (SAR) studies.
• Diagnostic Kit Manufacturing: Incorporated as a calibrated antigen in enzyme-linked immunosorbent assay (ELISA) kits and other immunoassays for research and clinical diagnostics.
• Academic & Institutional Research: A vital tool for universities and research institutes studying cardiovascular biology, neuropharmacology, and inflammatory processes.

Basic Information

Product Name	H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Oh Acetate Salt
CAS No.	23815-87-4
Molecular Formula	C37H58N12O10 • xC2H4O2
Molecular Weight	830.94 g/mol (free base)
Synonyms	Bradykinin (1-7); Arg-Pro-Pro-Gly-Phe-Ser-Pro-OH acetate; H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-OH • AcOH; Des-Phe8-Arg9-Bradykinin acetate salt; RPPGFSP-OH acetate; BK (1-7) acetate; Bradykinin heptapeptide fragment acetate; Kinin metabolite acetate salt
EINECS	Contact for details

Quality Control

Every batch of our H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Oh Acetate Salt is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and content. Our quality commitment supports your need for reliable and consistent materials in critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0% (by weight)
Water Content (KF)	≤ 8.0%
Acetate Content (IC)	5.0% - 15.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.