Description

7-Chloro-1-Methyl-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid is a high-purity pharmaceutical intermediate and organic building block of significant commercial importance. This compound serves as a critical precursor in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly within the quinolone and fluoroquinolone antibiotic classes. It is essential for research and development laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of quinolone and fluoroquinolone antibacterial agents.
• Active Pharmaceutical Ingredient (API) Development: Used in R&D for creating new antibiotic candidates and other therapeutic molecules.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds in organic chemistry.
• Biochemical Research: Employed in studies targeting bacterial DNA gyrase and topoisomerase IV enzymes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production.
• Reference Standard: Used as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	7-Chloro-1-Methyl-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid
CAS No.	23789-96-0
Molecular Formula	C11H8ClNO3
Molecular Weight	237.64 g/mol
Synonyms	7-Chloro-1-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Methyl-7-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 7-Chloro-1-methyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; 3-Quinolinecarboxylic acid, 7-chloro-1,4-dihydro-1-methyl-4-oxo-; 7-Chloro-1-methyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 7-Chloro-1-methyl-4-oxo-1,4-dihydro-3-quinolincarboxylic acid; 7-Chloro-1-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate (anion form).
EINECS	Contact for details

Quality Control

Our 7-Chloro-1-Methyl-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid is manufactured under a strict quality management system. We provide material suitable for pharmaceutical R&D and synthesis, with typical purity levels exceeding 98% (HPLC). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Specifications can be developed to meet specific customer requirements, including compliance with ICH guidelines for residual solvents and heavy metals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.