Description

L-Erythrono-1,4-Lactone is a chiral lactone derivative of erythritol, serving as a versatile and high-value building block in organic synthesis. Its significance lies in its role as a key chiral intermediate for the production of pharmaceuticals, fine chemicals, and complex natural products. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemistry is critical for product efficacy and performance.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of antiviral drugs, nucleoside analogs, and other active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the preparation of complex molecules, including natural products, flavors, and fragrances requiring specific stereochemistry.
• Agrochemical Research: Acts as a building block for developing novel pesticides and herbicides with targeted biological activity.
• Biochemical Research: Employed in studies of carbohydrate metabolism and as a precursor for labeled compounds in metabolic pathway analysis.
• Polymer Chemistry: Can be utilized as a monomer or co-monomer for creating novel biodegradable or functional polymers.
• Cosmetic Ingredients: Serves as a starting material for synthesizing specialty humectants and skin-conditioning agents.

Basic Information

Product Name	L-Erythrono-1,4-Lactone
CAS No.	23732-40-3
Molecular Formula	C4H6O4
Molecular Weight	118.09 g/mol
Synonyms	(2R,3S)-2,3,4-Trihydroxybutanoic acid γ-lactone; L-(-)-Erythrono-1,4-lactone; (3S,4R)-Dihydroxybutyrolactone; L-Threono-1,4-lactone (enantiomer); Erythritol anhydride; L-Erythronolactone; (-)-Erythrono-1,4-lactone
EINECS	Contact for details

Quality Control

Our L-Erythrono-1,4-Lactone is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available for every batch upon request, ensuring full traceability and compliance with your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.