Description

2'-C-Methyl-, 2',3',5'-Tribenzoateuridine is a specialized nucleoside analog derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and intermediate for the synthesis of novel therapeutic agents, particularly in the antiviral and anticancer domains. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing next-generation nucleotide-based drugs.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of modified nucleoside antiviral and anticancer prodrugs.
• Biochemical Research: Used in studies investigating RNA synthesis inhibition and viral polymerase mechanisms.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2'-C-Methyl-, 2',3',5'-Tribenzoateuridine
CAS No.	23643-36-9
Molecular Formula	C31H26N2O6
Molecular Weight	522.55 g/mol
Synonyms	2'-C-Methyluridine 2',3',5'-tribenzoate; 2'-C-Methyl-2',3',5'-tri-O-benzoyluridine; 1-[(2R,3R,4R,5R)-3,4-Bis(benzoyloxy)-5-(benzoyloxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione; 2'-C-Methyl-2',3',5'-tri-O-benzoyl-β-D-ribofuranosyluracil; Tribenzoyl-2'-C-methyluridine; 2'-Methyl-2',3',5'-tribenzoyluridine
EINECS	Contact for details

Quality Control

Our 2'-C-Methyl-, 2',3',5'-Tribenzoateuridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.