Description

H-His-Ser-βna CAS NO 23509-29-7 is a synthetic tripeptide derivative, specifically a modified sequence containing histidine, serine, and β-naphthylalanine. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential role in studying enzyme-substrate interactions and as a building block for novel bioactive peptides. It serves as a critical intermediate for researchers and manufacturers in the fields of medicinal chemistry and peptide-based drug discovery, where precise molecular structure is paramount for biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor analog in enzymatic studies to investigate protease mechanisms and kinetics.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new therapeutic agents with optimized properties.
• Peptide Library Synthesis: A valuable component for creating diverse peptide libraries used in high-throughput screening for drug discovery.
• Reference Standard: Utilized as a certified reference material (CRM) for analytical method development and quality control in peptide analysis.

Basic Information

Product Name	H-His-Ser-βna
CAS No.	23509-29-7
Molecular Formula	C₂₀H₂₃N₅O₅
Molecular Weight	413.43 g/mol
Synonyms	L-Histidyl-L-seryl-3-(2-naphthyl)-L-alanine; Histidyl-seryl-β-(2-naphthyl)alanine; H-His-Ser-β(2-Nal)-OH; H-His-Ser-(2-Nal)-OH; Tripeptide sequence with β-naphthylalanine; His-Ser-βna peptide; 23509-29-7; N-(N-L-Histidyl-L-seryl)-3-(2-naphthyl)-L-alanine
EINECS	Contact for details

Quality Control

Our H-His-Ser-βna is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and chiral purity analysis to ensure structural integrity. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Chiral Purity	≥ 99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.