Description

Boc-Cholecystokinin Octapeptide (3-8) is a protected synthetic fragment of the gastrointestinal hormone cholecystokinin. This peptide is a critical research-grade intermediate for the study of CCK receptor binding, signal transduction, and the development of diagnostic or therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neurogastroenterology and metabolic disorders.

Application

• Biochemical Research: A key tool for investigating the structure-activity relationship (SAR) of cholecystokinin and its interaction with CCK-A and CCK-B receptors.
• Pharmaceutical Development: Serves as a crucial synthetic intermediate in the preparation of longer CCK peptide analogs and potential drug candidates.
• Neuroscience Studies: Used in research models to understand the role of CCK in satiety, anxiety, pain perception, and dopaminergic pathways.
• Diagnostic Agent Synthesis: Acts as a precursor for radiolabeled (e.g., with 125I or 99mTc) peptides used in imaging and diagnostic assays.
• Enzyme Substrate: Employed in studies of peptidase and protease activity relevant to CCK metabolism.
• Reference Standard: Used as a high-purity standard in analytical methods (HPLC, MS) for quality control of related peptide products.

Basic Information

Product Name	Boc-Cholecystokinin Octapeptide (3-8)
CAS No.	23446-11-9
Molecular Formula	C53H74N10O15S
Molecular Weight	1123.3 g/mol
Synonyms	Boc-CCK-8 (3-8); Boc-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2; tert-Butyloxycarbonyl-Cholecystokinin Octapeptide Fragment 26-33 Amide; CCK-8 (26-33), Boc-; Boc-Sincalide (3-8) fragment; Cholecystokinin (26-33), N-[(1,1-dimethylethoxy)carbonyl]-; CCK Octapeptide, Boc-protected
EINECS	Contact for details

Quality Control

Our Boc-Cholecystokinin Octapeptide (3-8) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized by advanced analytical techniques including HPLC, MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with molecular formula
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ±10% of theoretical values

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.