Description

Boc-Met-Gly-Osu CAS NO 23446-04-0 is a protected amino acid derivative, specifically an N-Boc-protected methionine-glycine dipeptide active ester. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled and efficient formation of peptide bonds. It is primarily used by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences industries for the development of novel therapeutic peptides, peptide hormones, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential coupling of amino acids to construct custom peptide sequences.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs targeting metabolic disorders, cancer, and infectious diseases.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carrier proteins.
• Biochemical Tool Development: Essential for creating labeled peptides, enzyme substrates, or inhibitors for proteomics and enzymology studies.
• Academic Research: Employed in university and institutional labs for fundamental studies in peptide chemistry, structure-activity relationships (SAR), and molecular biology.
• Custom Peptide Service Providers: A fundamental reagent for CROs and CDMOs offering bespoke peptide manufacturing services.

Basic Information

Product Name	Boc-Met-Gly-Osu
CAS No.	23446-04-0
Molecular Formula	C17H27N3O7S
Molecular Weight	417.48 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-methionylglycine N-hydroxysuccinimide ester; Boc-Met-Gly-OSu; Boc-L-Methionylglycine N-succinimidyl ester; N-Boc-Methionine-Glycine-OSu; N-α-Boc-L-methionylglycine N-hydroxysuccinimide ester; tert-Butyloxycarbonylmethionylglycine succinimidyl ester; Boc-Met-Gly-O-Su; (2,5-Dioxopyrrolidin-1-yl) 2-[(2-{[(2S)-2-[(tert-butoxycarbonyl)amino]-4-(methylsulfanyl)butanoyl]amino}acetyl)amino]acetate
EINECS	Contact for details

Quality Control

Our Boc-Met-Gly-Osu is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.