Description

n-Epsilon,n-Epsilon,n-ε-Trimethyllysine is a modified amino acid derivative characterized by the presence of three methyl groups on the epsilon nitrogen of lysine. This compound serves as a crucial biochemical precursor and research standard in the study of protein methylation and epigenetic regulation. It is primarily utilized by research institutions, pharmaceutical developers, and manufacturers of high-purity biochemicals for advanced life science applications.

Application

• Biochemical Research Standard: Used as a high-purity reference compound in mass spectrometry and chromatography for the study of post-translational modifications.
• Enzymology Studies: Acts as a substrate or inhibitor in assays for methyltransferases and demethylases involved in epigenetic pathways.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel therapeutic agents targeting epigenetic mechanisms.
• Nutritional Science Research: Investigated for its role as a metabolic intermediate in carnitine biosynthesis and related pathways.
• Diagnostic Reagent Manufacturing: Incorporated into the production of calibrators and controls for clinical assays measuring methylation status.
• Cell Culture & Media Supplements: Used in specialized cell culture media for research requiring controlled methylation environments.

Basic Information

Product Name	n-Epsilon,n-Epsilon,n-ε-Trimethyllysine
CAS No.	23284-33-5
Molecular Formula	C9H20N2O2
Molecular Weight	188.27 g/mol
Synonyms	N6,N6,N6-Trimethyl-L-lysine; Trimethyllysine; TML; L-N6,N6,N6-Trimethyllysine; (2S)-2-Amino-6-(trimethylammonio)hexanoate; 2-Amino-6-(trimethylammonio)hexanoic acid; N-ε-Trimethyllysine; N6-Trimethyl-L-lysine
EINECS	245-559-8

Quality Control

Our n-Epsilon,n-Epsilon,n-ε-Trimethyllysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with detailed results for all critical parameters, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.