Description

n-Acetyl-3-Iodo-L-Tyrosine, Monohydrate is a chemically modified, iodinated derivative of the essential amino acid L-tyrosine. This compound is a critical building block and precursor in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel bioactive molecules, including potential thyroid hormone analogs and radiopharmaceuticals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel thyroid hormone analogs and receptor ligands for therapeutic research.
• Radiopharmaceutical Development: Serves as a precursor for iodine-123 or iodine-131 labeled compounds used in diagnostic imaging and targeted radiotherapy.
• Biochemical Research: Used in enzyme inhibition studies, metabolic pathway analysis, and as a substrate or inhibitor in studies related to tyrosine kinases and phosphatases.
• Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships, particularly where tyrosine modification is required.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	n-Acetyl-3-Iodo-L-Tyrosine, Monohydrate
CAS No.	23277-49-8
Molecular Formula	C11H12INO5 • H2O
Molecular Weight	383.13 g/mol (Monohydrate)
Synonyms	3-Iodo-N-acetyl-L-tyrosine Monohydrate; N-Acetyl-3-iodotyrosine Monohydrate; N-Acetyl-O-(3-iodo)-L-tyrosine Hydrate; Ac-3-Iodo-Tyr-OH • H2O; (2S)-2-Acetamido-3-(4-hydroxy-3-iodophenyl)propanoic acid Monohydrate; 3-Iodo-N-acetyltyrosine Monohydrate; L-Tyrosine, N-acetyl-3-iodo-, monohydrate
EINECS	Contact for details

Quality Control

Our n-Acetyl-3-Iodo-L-Tyrosine, Monohydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and development use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	4.0% - 6.5%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.