Description

(3R)-10-Amino-3,4,5,6-Tetrahydro-4β,5β-Dihydroxy-3β,6β-Epoxy-2H,8H-Pyrimido[6,1-B][1,3]Oxazocin-8-One CAS NO 23276-37-1 is a complex, high-purity heterocyclic compound characterized by its unique fused ring system containing amino, hydroxy, and epoxy functional groups. This specific stereochemistry and functional array make it a valuable advanced pharmaceutical intermediate for the synthesis of novel active ingredients. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• Antiviral Drug Research: Potential precursor in the development of nucleoside/nucleotide analog-based antiviral medications.
• Oncology Research: Used in constructing complex molecules for targeted cancer therapies and enzyme inhibitors.
• Chemical Biology & Proteomics: Acts as a specialized scaffold or linker in the design of chemical probes for studying biological pathways.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex active pharmaceutical ingredients (APIs).
• Academic & Contract Research: Essential for synthetic organic chemistry research in universities and CROs (Contract Research Organizations) focusing on heterocyclic chemistry.

Basic Information

Item	Details
Product Name	(3R)-10-Amino-3,4,5,6-Tetrahydro-4β,5β-Dihydroxy-3β,6β-Epoxy-2H,8H-Pyrimido[6,1-B][1,3]Oxazocin-8-One
CAS No.	23276-37-1
Molecular Formula	C10H12N4O5
Molecular Weight	268.23 g/mol
Synonyms	10-Amino-3,4,5,6-tetrahydro-4b,5b-dihydroxy-3b,6b-epoxy-2H,8H-pyrimido[6,1-b][1,3]oxazocin-8-one; (3R)-form; Pyrimidooxazocinone derivative; 23276-37-1; 10-Amino-3,4,5,6-tetrahydro-4b,5b-dihydroxy-3b,6b-epoxy-2H,8H-pyrimido[6,1-b][1,3]oxazocin-8-one (3R)-; 1,3-Oxazocino[6,1-b]pyrimidine derivative
EINECS	Contact for details

Quality Control

Our (3R)-10-Amino-3,4,5,6-Tetrahydro-4β,5β-Dihydroxy-3β,6β-Epoxy-2H,8H-Pyrimido[6,1-B][1,3]Oxazocin-8-One is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.