Description

2-Methyl-L-Phenylalanine Monohydrate is a non-proteinogenic amino acid derivative of significant interest in advanced chemical synthesis. This compound matters as a crucial chiral building block for the development of novel pharmaceuticals and bioactive peptides. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for applications in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for metabolic and neurological drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a modified phenylalanine residue, altering peptide stability and bioactivity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway research.
• Asymmetric Catalysis: Employed as a ligand or precursor for chiral catalysts in asymmetric synthesis.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Nutraceutical R&D: Investigated for potential applications in the development of specialized amino acid supplements.

Basic Information

Product Name	2-Methyl-L-Phenylalanine Monohydrate
CAS No.	23239-35-2
Molecular Formula	C₁₀H₁₃NO₂ • H₂O
Molecular Weight	197.22 g/mol (Anhydrous basis: 179.22)
Synonyms	(S)-2-Amino-2-methyl-3-phenylpropanoic acid monohydrate; L-2-Methylphenylalanine monohydrate; (2S)-2-Amino-2-methyl-3-phenylpropanoic acid hydrate; 2-Methyl-L-α-aminohydrocinnamic acid monohydrate; H-2-MePhe-OH • H₂O; 2-Methyl-L-β-phenylalanine monohydrate
EINECS	Contact for details

Quality Control

Our 2-Methyl-L-Phenylalanine Monohydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification and monohydrate content confirmation, to ensure it meets stringent specifications for research and cGMP-grade applications. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture uptake and ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Water Content (KF)	7.0 - 9.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.