Description

n-Acetyl-S-(3-Hydroxypropyl)Cysteine is a specialized cysteine derivative, a key intermediate in the synthesis of advanced pharmaceutical compounds and biochemical research reagents. Its value lies in its functionalized structure, which combines the reactive thiol group of cysteine with protective and solubilizing moieties, making it a versatile building block. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those developing novel therapeutics, prodrugs, or conducting metabolic studies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of specialized active pharmaceutical ingredients (APIs) and prodrugs, particularly those targeting metabolic pathways or requiring controlled release.
• Biochemical Research: Used as a standard or reagent in studies of cysteine metabolism, protein modification, and redox biology due to its acetylated and hydroxypropyl-protected thiol group.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical and clinical laboratories.
• Precursor for Conjugates: Utilized in the development of drug conjugates, peptide mimetics, and other complex molecules where a functionalized cysteine residue is required.
• Metabolite Studies: Employed in research investigating the metabolic fate and detoxification pathways of related sulfur-containing compounds.

Basic Information

Product Name	n-Acetyl-S-(3-Hydroxypropyl)Cysteine
CAS No.	23127-40-4
Molecular Formula	C8H15NO4S
Molecular Weight	221.27 g/mol
Synonyms	N-Acetyl-3-(3-hydroxypropylthio)alanine; N-Acetyl-S-(3-hydroxypropyl)-L-cysteine; 2-Acetamido-3-(3-hydroxypropylthio)propanoic acid; Mercapturic Acid Derivative; 3-HPMA Precursor; N-Acetyl-S-(3-hydroxypropyl)cysteine; N-Acetyl-S-(3-hydroxypropyl)-DL-cysteine; Acetylcysteine S-(3-hydroxypropyl) derivative
EINECS	Contact for details

Quality Control

Our n-Acetyl-S-(3-Hydroxypropyl)Cysteine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.