Description

5-Fluoroindole-3-Carboxylic Acid is a high-purity fluorinated indole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in modulating the biological activity and physicochemical properties of target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of a fluorine atom is a key strategic modification.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides and herbicides, where fluorine enhances stability and bioactivity.
• Biochemical Research: Serves as a precursor for fluorescent probes or enzyme inhibitors used in biochemical assays and diagnostic research.
• Material Science: Employed in the synthesis of specialized organic electronic materials and advanced polymers.
• Academic & R&D: A versatile starting material for methodological studies in organic chemistry and novel heterocyclic compound libraries.

Basic Information

Product Name	5-Fluoroindole-3-Carboxylic Acid
CAS No.	23077-43-2
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	5-Fluoro-1H-indole-3-carboxylic acid; 3-Carboxy-5-fluoroindole; 5-Fluoroindole-3-carboxylic acid; 5-Fluoro-3-indolecarboxylic acid; 5-Fluoro-1H-indole-3-carboxylic acid; 23077-43-2; 5-Fluoroindol-3-carbonsäure (German); Acide 5-fluoro-1H-indole-3-carboxylique (French)
EINECS	Contact for details

Quality Control

Our 5-Fluoroindole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatograms are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	250 - 255 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.