Description

1H-Indole-3-Carboxylic Acid,4-Fluoro- is a high-value fluorinated indole derivative, a crucial building block in advanced organic synthesis. Its core value lies in enabling the precise introduction of both the indole scaffold and a fluorine atom, which are pivotal for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly in oncology, neurology, and anti-inflammatory research.
• Agrochemical Synthesis: Used to develop novel pesticides and herbicides with enhanced efficacy and environmental profiles.
• Biochemical Research: Serves as a probe or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Material Science: Potential monomer or precursor for specialized polymers and organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development.

Basic Information

Product Name	1H-Indole-3-Carboxylic Acid,4-Fluoro-
CAS No.	23077-42-1
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	4-Fluoro-1H-indole-3-carboxylic acid; 4-Fluoroin dole-3-carboxylic acid; 4-Fluoroindole-3-carboxylic acid; 4-Fluoro-1H-indole-3-carboxylic acid; 4-Fluoro-3-indolecarboxylic acid; 4-Fluoro-3-carboxyindole; 4-Fluoroindole-3-carboxylate; 4-Fluoro-1H-indole-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-3-Carboxylic Acid,4-Fluoro- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all critical quality attributes. We support development and commercial projects with material that meets the exacting standards required for pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (High Purity Grades)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.