Description

L-Glutamic Acid-Ul-14C is a uniformly carbon-14 labeled derivative of the essential amino acid L-glutamic acid, with a molecular weight of 147.1. This isotopically labeled compound is a critical tool for metabolic pathway tracing and biochemical research, enabling precise tracking of glutamic acid's fate in biological systems. It is primarily utilized by researchers and scientists in the pharmaceutical, biotechnology, and agricultural sectors for advanced studies in neurotransmission, protein synthesis, and nitrogen metabolism.

Application

• Metabolic Flux Analysis: Used as a tracer to study the Krebs cycle, amino acid metabolism, and gluconeogenesis pathways in cell cultures, tissues, and whole organisms.
• Neuropharmacology Research: Essential for investigating the role of glutamic acid as a primary excitatory neurotransmitter, including studies on receptor binding, uptake, and synaptic plasticity.
• Drug Discovery & Development: Employed in ADME (Absorption, Distribution, Metabolism, Excretion) studies to label and track potential drug candidates or their metabolites.
• Agricultural Biochemistry: Applied in research on plant nitrogen assimilation and amino acid biosynthesis to improve crop yield and nutrient efficiency.
• Protein & Peptide Labeling: Serves as a building block for synthesizing radiolabeled proteins and peptides for use in binding assays and structural studies.
• Diagnostic Agent Development: A potential precursor in the development of radiolabeled diagnostic probes for imaging techniques like PET (Positron Emission Tomography), pending specific formulation.

Basic Information

Item	Detail
Product Name	L-Glutamic Acid-Ul-14C
CAS No.	23009-64-5
Molecular Formula	C5H914NO4 *
Molecular Weight	147.1 g/mol
Synonyms	(2S)-2-Aminopentanedioic-Ul-14C Acid; L-Glutamic-Ul-14C Acid; (S)-2-Aminoglutaric-Ul-14C Acid; GLU-Ul-14C; Uniformly Labeled Carbon-14 L-Glutamic Acid; [U-14C]-L-Glutamic Acid
EINECS	Contact for details

* Formula indicates uniform labeling with Carbon-14; exact atomic composition may vary.

Quality Control

Every batch of our L-Glutamic Acid-Ul-14C is manufactured and analyzed under strict quality systems. We guarantee high radiochemical purity and specific activity consistency, supported by comprehensive analytical documentation. A detailed Certificate of Analysis (COA) is provided with each shipment, containing results for radiochemical purity (by HPLC), specific activity, chemical purity, and solvent content. Our production adheres to cGMP guidelines where applicable for research materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Store in accordance with all local and national regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 98%
Specific Activity	Contact for details (mCi/mmol)
Chemical Purity (HPLC)	≥ 95%
Solvent Content (Residual)	Meets internal specifications

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.