Description

H-Ile-Phe-Oh is a high-purity dipeptide building block, specifically the L-isoleucyl-L-phenylalanine derivative. This compound is a critical intermediate for advanced peptide synthesis, offering precise structural control for research and development. It is essential for pharmaceutical chemists, biotech researchers, and fine chemical manufacturers engaged in creating novel therapeutic peptides, enzyme substrates, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block for the solid-phase and solution-phase synthesis of complex therapeutic peptides targeting metabolic and neurological disorders.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to investigate protease specificity and function.
• Cosmetic Peptide Synthesis: Serves as a precursor for bioactive peptides used in anti-aging and skin-repair cosmetic formulations.
• Nutraceutical Development: Employed in the design and production of bioactive peptide supplements for health and wellness applications.
• Academic & Institutional Research: A fundamental reagent for university and institutional labs studying peptide structure-activity relationships (SAR) and molecular recognition.
• Custom Peptide Service Providers: A core material for CROs and CDMOs offering bespoke peptide manufacturing services to the life sciences industry.

Basic Information

Product Name	H-Ile-Phe-Oh
CAS No.	22951-98-0
Molecular Formula	C15H22N2O3
Molecular Weight	278.35 g/mol
Synonyms	L-Isoleucyl-L-phenylalanine; Ile-Phe; Isoleucine Phenylalanine Dipeptide; H-Ile-Phe-OH; N-(3-Methylpentanoyl)-L-phenylalanine; (2S)-2-[[(2S,3S)-2-Amino-3-methylpentanoyl]amino]-3-phenylpropanoic acid; L-Phenylalanine, N-L-isoleucyl-; FA-Ile-Phe
EINECS	Contact for details

Quality Control

Our H-Ile-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. The container should be kept tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-15° to -25° (c=1 in AcOH)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%
Single Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.