Description

(2S,E)-1-[5-Amino-1-(1,2,3,4-Tetrahydro-5-Hydroxymethyl-2,4-Dioxopyrimidin-1-Yl)-1,5-Dideoxy-β-D-Allofuranulonoyl]-3-Ethylidene-2-Azetidinecarboxylic Acid is a high-purity, structurally complex nucleoside analog derivative. This compound is of significant value as a key pharmaceutical intermediate or advanced building block in the synthesis of novel antiviral and anticancer agents. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral drugs.
• Anticancer Agent Research: Serves as a building block for developing targeted cancer therapies that interfere with DNA/RNA synthesis.
• Biochemical Research: Used in enzymatic studies and as a substrate analog to investigate metabolic pathways.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs).
• Protease Inhibitor Synthesis: Potential use in constructing the azetidinecarboxylic acid core found in certain protease inhibitors.

Basic Information

Product Name	(2S,E)-1-[5-Amino-1-(1,2,3,4-Tetrahydro-5-Hydroxymethyl-2,4-Dioxopyrimidin-1-Yl)-1,5-Dideoxy-β-D-Allofuranulonoyl]-3-Ethylidene-2-Azetidinecarboxylic Acid
CAS No.	22886-33-5
Molecular Formula	C16H20N4O9
Molecular Weight	412.35 g/mol
Synonyms	3-Ethylidene-2-azetidinecarboxylic acid, 1-[5-amino-1-(1,2,3,4-tetrahydro-5-(hydroxymethyl)-2,4-dioxo-1-pyrimidinyl)-1,5-dideoxy-β-D-allofuranuronoyl]-; 1-[(2S,5R)-5-Amino-1-(1,2,3,4-tetrahydro-5-(hydroxymethyl)-2,4-dioxopyrimidin-1-yl)-1,5-dideoxy-β-D-allofuranuronoyl]-3-ethylideneazetidine-2-carboxylic acid; (2S,E)-1-[(2S,5R)-5-Amino-1-(1,2,3,4-tetrahydro-5-(hydroxymethyl)-2,4-dioxopyrimidin-1-yl)-1,5-dideoxy-β-D-allofuranuronoyl]-3-ethylideneazetidine-2-carboxylic acid; Nucleoside Azetidine Derivative; 22886-33-5; 3-Ethylideneazetidine-2-carboxylic acid derivative.
EINECS	Contact for details

Quality Control

Our (2S,E)-1-[5-Amino-1-(1,2,3,4-Tetrahydro-5-Hydroxymethyl-2,4-Dioxopyrimidin-1-Yl)-1,5-Dideoxy-β-D-Allofuranulonoyl]-3-Ethylidene-2-Azetidinecarboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.