Description

Cyclo(L-Ala-D-Trp-) CAS NO 22839-23-2 is a synthetic cyclic dipeptide, also known as a diketopiperazine (DKP), composed of L-alanine and D-tryptophan residues. This specific stereochemistry makes it a valuable chiral building block and a scaffold of significant interest in pharmaceutical research and development. It is primarily utilized by research institutions and companies in the life sciences sector for exploring novel therapeutic agents and studying peptide conformation and bioactivity.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of more complex bioactive molecules and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop enzyme inhibitors or receptor modulators.
• Peptidomimetics: Acts as a stable, conformationally restricted template to mimic natural peptide structures for enhanced metabolic stability.
• Biochemical Tool Compound: Employed in academic and industrial research to investigate cell signaling pathways and biological mechanisms.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Cyclo(L-Ala-D-Trp-)
CAS No.	22839-23-2
Molecular Formula	C14H15N3O2
Molecular Weight	257.29 g/mol
Synonyms	Cyclo(L-alanyl-D-tryptophanyl); Cyclo(L-Ala-D-Trp); L-Ala-D-Trp Diketopiperazine; 3-[(1H-Indol-3-yl)methyl]-6-methylpiperazine-2,5-dione; DKP (L-Ala-D-Trp); Cyclo(alanine-tryptophan); (3S,6R)-3-(1H-Indol-3-ylmethyl)-6-methylpiperazine-2,5-dione
EINECS	Contact for details

Quality Control

Our Cyclo(L-Ala-D-Trp-) is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.