Description

3-Hydroxyhalazepam is a key benzodiazepine metabolite and a significant pharmaceutical intermediate. This compound is essential for analytical research and development within the pharmaceutical and forensic science sectors. It is primarily utilized by research institutions, pharmaceutical manufacturers, and analytical laboratories for method development, reference standards, and metabolic studies.

Application

• Pharmaceutical intermediate for the synthesis of active pharmaceutical ingredients (APIs).
• Analytical reference standard for quality control and method validation in HPLC and LC-MS.
• Metabolite standard for pharmacokinetic and drug metabolism studies.
• Research chemical for neuropharmacology and benzodiazepine receptor studies.
• Forensic analysis standard for the identification and quantification of substances.
• Impurity standard for the characterization and control of related substances in drug substances.

Basic Information

Product Name	3-Hydroxyhalazepam
CAS No.	22753-75-9
Molecular Formula	C17H14ClFN2O2
Molecular Weight	332.76 g/mol
Synonyms	7-Chloro-5-(2-fluorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Halazepam 3-Hydroxy Metabolite; 3-OH-Halazepam; 7-Chloro-1,3-dihydro-5-(2-fluorophenyl)-3-hydroxy-2H-1,4-benzodiazepin-2-one; 3-Hydroxy-7-chloro-5-(o-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 3-Hydroxyhalazepam is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR to ensure it meets high-purity standards suitable for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.