Description

H-Gly-Gly-Phe-Phe-Oet is a synthetic tetrapeptide derivative, specifically an ethyl ester, featuring a glycyl-glycyl-phenylalanyl-phenylalanine sequence. This compound is a valuable intermediate in peptide synthesis and biochemical research, offering a defined structure for studying enzyme-substrate interactions and metabolic pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing novel bioactive peptides and protease inhibitors.

Application

• Biochemical Research: Used as a standard or substrate in enzymatic studies, particularly for investigating the activity and inhibition mechanisms of proteases like chymotrypsin and carboxypeptidase.
• Pharmaceutical Intermediate: Serves as a key building block in the solid-phase or solution-phase synthesis of more complex therapeutic peptides.
• Proteomics & Diagnostics: Can be employed in the development of assay kits and diagnostic tools for measuring specific protease activity in biological samples.
• Academic Research: Utilized in university and institutional labs for fundamental studies on peptide stability, folding, and receptor-ligand interactions.

Basic Information

Product Name	H-Gly-Gly-Phe-Phe-Oet
CAS No.	22732-97-4
Molecular Formula	C24H29N4O5
Molecular Weight	453.51 g/mol
Synonyms	Glycyl-glycyl-L-phenylalanyl-L-phenylalanine ethyl ester; GGFP-OEt; H-Gly-Gly-Phe-Phe-OEt; Ethyl N-[(2S)-1-[[(2S)-1-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-phenyl-1-oxopropan-2-yl]amino]-3-phenyl-1-oxopropan-2-yl]carbamate; Tetrapeptide GGFP-OEt; L-Phenylalanine, glycylglycyl-L-phenylalanyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our H-Gly-Gly-Phe-Phe-Oet is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, chiral analysis to confirm stereochemical integrity, and identity confirmation via mass spectrometry (MS) and infrared spectroscopy (IR). Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.