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4-Methyl Hydrogen D-Aspartate Hydrochloride CAS NO 22728-89-8


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CAS No.:22728-89-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Methyl Hydrogen D-Aspartate Hydrochloride is a high-purity, non-natural amino acid derivative used as a critical chiral building block and research chemical. This compound is valued for its role in the synthesis of peptides and other bioactive molecules, where stereochemical purity is paramount. It serves researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for advanced synthesis and biochemical studies.

Application

  • Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic peptides and enzyme inhibitors.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving glutamate receptors or aspartate-specific enzymes.
  • Peptide Synthesis: An essential building block for the solid-phase or solution-phase synthesis of custom peptides with specific stereochemical configurations.
  • Neuroscience Research: Investigated for its potential activity as an NMDA receptor modulator or in studies of neurotransmission.
  • Fine Chemical Production: Employed in the multi-step synthesis of complex organic molecules requiring high enantiomeric purity.
  • Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in laboratories.

Basic Information

Product Name 4-Methyl Hydrogen D-Aspartate Hydrochloride
CAS No. 22728-89-8
Molecular Formula C5H9NO4 • HCl
Molecular Weight 183.59 g/mol
Synonyms D-4-Methyl Aspartic Acid Hydrochloride; (2R)-2-Amino-2-methylbutanedioic acid hydrochloride; D-2-Amino-2-methylsuccinic acid hydrochloride; D-α-Methylaspartic acid hydrochloride; (R)-2-Amino-2-methylsuccinic acid hydrochloride; D-2-Methylaspartic Acid Hydrochloride; H-D-Asp(4-Me)-OH • HCl
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Quality Control

Our 4-Methyl Hydrogen D-Aspartate Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥98.0%
Chiral Purity (HPLC) ≥99.0% (D-isomer)
Loss on Drying ≤1.0%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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