Description

Boc-Lys(4-Nitro-Z)-Oh is a protected amino acid derivative, specifically a lysine residue with orthogonal protecting groups. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of complex peptides. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing peptide-based therapeutics, diagnostics, and research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of lysine into peptide chains.
• Pharmaceutical Research: Synthesis of peptide drug candidates, including antimicrobial peptides and hormone analogs.
• Bioconjugation: Used to introduce functional handles (via the deprotected amine) for linking peptides to other molecules, dyes, or surfaces.
• Combinatorial Chemistry: Building block for creating libraries of peptide compounds for high-throughput screening.
• Academic & Industrial R&D: Fundamental research in peptide chemistry, structure-activity relationships (SAR), and protein engineering.

Basic Information

Product Name	Boc-Lys(4-Nitro-Z)-Oh
CAS No.	22601-53-2
Molecular Formula	C₂₀H₂₉N₃O₇
Molecular Weight	423.46 g/mol
Synonyms	Nα-Boc-Nε-(4-Nitrobenzyloxycarbonyl)-L-lysine; Boc-Lys(Nε-Z(4-NO₂))-OH; (2S)-6-[[(4-Nitrophenyl)methoxy]carbonylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid; Nα-tert-Butoxycarbonyl-Nε-(4-nitrobenzyloxycarbonyl)-L-lysine; Boc-Lys(Z(4-NO₂))-OH; Boc-L-Lys(4-NO₂-Z)-OH; N-Boc-N'-Z(4-NO₂)-L-lysine
EINECS	Contact for details

Quality Control

Our Boc-Lys(4-Nitro-Z)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic methods for structural confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Specific Rotation	-10.0° to -12.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.