Description

3-Mercapto-Dl-Valine Hydrochloride is a specialized amino acid derivative of significant interest in advanced chemical synthesis and pharmaceutical research. This compound is valued for its unique thiol (-SH) functional group, which makes it a versatile building block for creating complex molecules and modifying peptides. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Peptide Modification: Used to introduce thiol groups into peptide chains for site-specific conjugation, labeling, or to create disulfide bridges that stabilize protein structures.
• Bioconjugation Chemistry: Serves as a linker or functional handle for attaching drugs, fluorescent probes, or other molecules to antibodies, proteins, or nanoparticles in bioconjugation applications.
• Research & Development: An essential reagent in academic and industrial R&D labs for studying enzyme mechanisms, protein engineering, and metabolic pathways.
• Precursor for Chelating Agents: Acts as a precursor in the synthesis of specialized chelating ligands used in metal catalysis or diagnostic imaging agents.

Basic Information

Product Name	3-Mercapto-Dl-Valine Hydrochloride
CAS No.	22572-05-0
Molecular Formula	C5H11NO2S • HCl
Molecular Weight	185.67 g/mol
Synonyms	DL-3-Mercaptovaline hydrochloride; 2-Amino-3-mercapto-3-methylbutanoic acid hydrochloride; 3-Mercaptovaline HCl; 3-Thiavaline hydrochloride; (±)-3-Mercaptovaline hydrochloride; 3-Methyl-3-sulfanylbutanoic acid hydrochloride (amino form); 3-Mercapto-DL-valine HCl
EINECS	Contact for details

Quality Control

Our 3-Mercapto-Dl-Valine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened for prolonged use to prevent oxidation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.