Description

2-Chloropyrimidine-4-Carboxamide is a versatile and high-value pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its primary importance lies in its role as a key synthetic intermediate for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those targeting kinases and other enzymes.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Ligand and Catalyst Preparation: Employed in the creation of specialized ligands for metal catalysis and coordination chemistry.
• Material Science: Potential building block for the synthesis of organic electronic materials and advanced polymers.

Basic Information

Product Name	2-Chloropyrimidine-4-Carboxamide
CAS No.	22536-66-9
Molecular Formula	C5H4ClN3O
Molecular Weight	157.56 g/mol
Synonyms	4-Carbamoyl-2-chloropyrimidine; 2-Chloro-4-pyrimidinecarboxamide; 2-Chloropyrimidine-4-carboxylic acid amide; 2-Chloro-4-carbamoylpyrimidine; 2-Chloro-4-pyrimidinecarboxylic acid amide; 22536-66-9; 2-Chloropyrimidine-4-carboxylic acid, amide
EINECS	Contact for details

Quality Control

Our 2-Chloropyrimidine-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.