Description

2-Chloro-4-Methoxy-6-Methylpyrimidine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactive chloro and methoxy substituents, which make it a critical intermediate for constructing complex molecular architectures. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery programs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the pyrimidine core is a common pharmacophore.
• Material Science Research: Serves as a precursor for creating specialized polymers, ligands, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the development of molecular probes, enzyme inhibitors, and tool compounds for biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical reactions.

Basic Information

Product Name	2-Chloro-4-Methoxy-6-Methylpyrimidine
CAS No.	22536-64-7
Molecular Formula	C6H7ClN2O
Molecular Weight	158.59 g/mol
Synonyms	2-Chloro-4-methoxy-6-methylpyrimidine; 6-Methyl-2-chloro-4-methoxypyrimidine; 4-Methoxy-6-methyl-2-chloropyrimidine; 2-Chloro-4-methoxy-6-methyl-1,3-diazine; Pyrimidine, 2-chloro-4-methoxy-6-methyl-; 22536-64-7 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methoxy-6-Methylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.