Description

2-Chloro-5-Phenyl-Pyrimidine is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the agrochemical, pharmaceutical, and material science industries, where it serves as a precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates.
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the pyrimidine core into more complex structures.
• Academic & R&D: A valuable reagent for methodological studies and the discovery of new chemical reactions in university and corporate laboratories.

Basic Information

Product Name	2-Chloro-5-Phenyl-Pyrimidine
CAS No.	22536-62-5
Molecular Formula	C10H7ClN2
Molecular Weight	190.63 g/mol
Synonyms	5-Phenyl-2-chloropyrimidine; 2-Chloro-5-phenylpyrimidine; 2-Chloro-5-phenyl-1,3-diazine; Pyrimidine, 2-chloro-5-phenyl-; (2-Chloropyrimidin-5-yl)benzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Phenyl-Pyrimidine is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.