Description

2-Pyrimidinemethanol, 5-Bromo- (8Ci,9Ci) CAS NO 22433-12-1 is a high-purity brominated pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with tailored biological and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, including kinase inhibitors, antiviral agents, and anticancer compounds.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitutions to introduce complex pyrimidine motifs.
• Bioconjugation & Probe Development: Useful for creating labeled compounds and molecular probes for biochemical and diagnostic applications.
• Academic & Contract Research: Critical for medicinal chemistry programs and discovery research in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	2-Pyrimidinemethanol, 5-Bromo- (8Ci,9Ci)
CAS No.	22433-12-1
Molecular Formula	C5H5BrN2O
Molecular Weight	189.01 g/mol
Synonyms	5-Bromo-2-pyrimidinemethanol; (5-Bromo-2-pyrimidinyl)methanol; 5-Bromo-2-(hydroxymethyl)pyrimidine; 5-Bromopyrimidine-2-methanol; 2-(Hydroxymethyl)-5-bromopyrimidine; 5-Bromo-2-pyrimidinecarbinol; 5-Bromopyrimidin-2-ylmethanol
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinemethanol, 5-Bromo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.