Description

3,6,8-Trimethylpyrido[3,4-D]Pyrimidin-4(3H)-One is a high-purity heterocyclic organic compound that serves as a critical advanced intermediate in modern chemical synthesis. Its value lies in its complex pyridopyrimidine core, which is a privileged scaffold for developing active pharmaceutical ingredients and specialty agrochemicals. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other enzymatic pathways.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and plant growth regulators that leverage the pyridopyrimidine structure for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for electron-transport or host materials in OLED device fabrication due to its rigid, conjugated structure.
• Ligand Synthesis in Catalysis: Employed to create sophisticated nitrogen-containing ligands for transition metal catalysts used in asymmetric synthesis.
• Biochemical Probe Development: Utilized in academic and industrial research to create molecular probes for studying biological processes and disease mechanisms.
• Fine Chemical Synthesis: Acts as a versatile intermediate for producing dyes, pigments, and other performance chemicals requiring complex heterocyclic cores.

Basic Information

Product Name	3,6,8-Trimethylpyrido[3,4-D]Pyrimidin-4(3H)-One
CAS No.	22389-79-3
Molecular Formula	C11H11N3O
Molecular Weight	201.23 g/mol
Synonyms	3,6,8-Trimethyl-4H-pyrido[3,4-d]pyrimidin-4-one; 3,6,8-Trimethylpyrido[3,4-d]pyrimidin-4(3H)-one; 4(3H)-Pyrimidinone, 3,6,8-trimethylpyrido[3,4-d]-; Pyrido[3,4-d]pyrimidin-4(3H)-one, 3,6,8-trimethyl-; 22389-79-3; 3,6,8-TMPP; Trimethylpyridopyrimidinone
EINECS	Contact for details

Quality Control

Every batch of 3,6,8-Trimethylpyrido[3,4-D]Pyrimidin-4(3H)-One is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles as measured by HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.