Description

2,6,8-Trimethylpyrido[3,4-D]Pyrimidin-4(3H)-One is a high-purity heterocyclic organic compound serving as a critical advanced intermediate in modern chemical synthesis. Its value lies in its complex pyridopyrimidine core, which is a privileged scaffold for developing novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This product is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators due to its bioactive heterocyclic structure.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex dyes, pigments, and functional materials.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	2,6,8-Trimethylpyrido[3,4-D]Pyrimidin-4(3H)-One
CAS No.	22378-52-5
Molecular Formula	C10H11N3O
Molecular Weight	189.21 g/mol
Synonyms	2,6,8-Trimethyl-3H-pyrido[3,4-d]pyrimidin-4-one; 2,6,8-Trimethyl-4(3H)-pyrido[3,4-d]pyrimidinone; 4(3H)-Pyrido[3,4-d]pyrimidinone, 2,6,8-trimethyl-; 2,6,8-Trimethylpyrido[3,4-d]pyrimidin-4-ol; NSC 163031
EINECS	Contact for details

Quality Control

Our 2,6,8-Trimethylpyrido[3,4-D]Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements for advanced intermediate use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.