Description

Triflubazam is a specialized benzodiazepine derivative with significant potential in pharmaceutical research and development. Its unique chemical structure makes it a valuable intermediate for synthesizing novel therapeutic agents targeting the central nervous system. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of anxiolytic and sedative-hypnotic medications. Triflubazam CAS NO 22365-40-8 is supplied to meet the stringent purity requirements of advanced chemical synthesis and analytical applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and new drug discovery.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Preclinical Studies: Employed in pharmacological research to investigate mechanisms of action related to GABAA receptor modulation.
• Chemical Synthesis: Utilized as a precursor for creating more complex molecules with potential therapeutic applications.

Basic Information

Product Name	Triflubazam
CAS No.	22365-40-8
Molecular Formula	C17H14ClF3N2O
Molecular Weight	354.75 g/mol
Synonyms	1-Methyl-5-phenyl-7-(trifluoromethyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione; 7-Chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 4-Oxide; Triflubazam; Ro 5-3027; CAS 22365-40-8
EINECS	Contact for details

Quality Control

Our Triflubazam is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and GC. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our quality commitment aligns with the standards expected for pharmaceutical research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to prevent contamination and moisture absorption. For long-term storage, consider conditions that minimize exposure to temperature fluctuations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.