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3β-[(6-Deoxy-β-D-Gulopyranosyl)Oxy]-5,11α,14-Trihydroxy-19-Oxo-5β-Card-20(22)-Enolide CAS NO 22333-73-9


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CAS No.:22333-73-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[(6-Deoxy-β-D-Gulopyranosyl)Oxy]-5,11α,14-Trihydroxy-19-Oxo-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. Its precise stereochemistry and functional groups make it an essential building block for developing novel therapeutic agents targeting cardiovascular functions. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of cardiac drugs and biochemical studies.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of specialized cardiac glycosides and related therapeutic compounds.
  • Biochemical Research: Used as a reference standard and active agent in studies of sodium-potassium ATPase inhibition and cardiac cell physiology.
  • Medicinal Chemistry: Serves as a core scaffold for the design and development of new drug candidates with potential inotropic activity.
  • Analytical Standard: Employed in HPLC, LC-MS, and NMR for method development, calibration, and quality control in pharmaceutical analysis.
  • Academic Research: Utilized in university and institutional labs for investigating the structure-activity relationships of steroidal compounds.

Basic Information

Product Name 3β-[(6-Deoxy-β-D-Gulopyranosyl)Oxy]-5,11α,14-Trihydroxy-19-Oxo-5β-Card-20(22)-Enolide
CAS No. 22333-73-9
Molecular Formula C29H42O10
Molecular Weight 550.64 g/mol
Synonyms Digitoxigenin 6-deoxy-β-D-guloside; 3β-[(6-Deoxy-β-D-gulopyranosyl)oxy]-5,11α,14-trihydroxy-19-oxo-5β-card-20(22)-enolide; 6-Deoxy-β-D-gulosyl digitoxigenin; 19-Oxodigitoxigenin 3-O-(6-deoxy-β-D-guloside); Card-20(22)-enolide, 3-[(6-deoxy-β-D-gulopyranosyl)oxy]-5,11,14-trihydroxy-19-oxo-, (3β,5β,11α)-; A cardiac glycoside aglycone derivative.
EINECS Contact for details

Quality Control

Our 3β-[(6-Deoxy-β-D-Gulopyranosyl)Oxy]-5,11α,14-Trihydroxy-19-Oxo-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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