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14-Hydroxy-3β-[[3-o-Methyl-4-(Methylamino)-2,4,6-Trideoxy-β-D-Ribo-Hexopyranosyl]Oxy]-5β,14β-Card-20(22)-Enolide CAS NO 22214-87-5
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CAS No.:22214-87-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
14-Hydroxy-3β-[[3-o-Methyl-4-(Methylamino)-2,4,6-Trideoxy-β-D-Ribo-Hexopyranosyl]Oxy]-5β,14β-Card-20(22)-Enolide is a high-purity, complex cardenolide glycoside of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate and reference standard for the synthesis and study of novel cardiac glycosides and related therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on cardiovascular drug discovery and development.
Application
- Pharmaceutical Intermediate: A key building block in the synthetic pathway for novel cardiac glycoside drugs.
- Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related active pharmaceutical ingredients (APIs).
- Biochemical Research: Employed in studies investigating the mechanism of action of cardenolides on sodium-potassium ATPase pumps.
- Preclinical Development: Serves as a starting material or comparator in the development of new therapeutic agents for heart failure and arrhythmias.
- Academic Research: Utilized in university and institutional labs for pharmacological and structure-activity relationship (SAR) studies.
Basic Information
| Product Name | 14-Hydroxy-3β-[[3-o-Methyl-4-(Methylamino)-2,4,6-Trideoxy-β-D-Ribo-Hexopyranosyl]Oxy]-5β,14β-Card-20(22)-Enolide |
| CAS No. | 22214-87-5 |
| Molecular Formula | C30H47NO8 |
| Molecular Weight | 549.70 g/mol |
| Synonyms | 3'-O-Methyladynerigenin β-D-ribo-hexopyranoside; 3'-O-Methyladynerigenin β-D-ribo-hexoside; 14-Hydroxy-3β-[(3-O-methyl-4-methylamino-2,4,6-trideoxy-β-D-ribo-hexopyranosyl)oxy]-5β,14β-card-20(22)-enolide; 3'-O-Methyladynerigenin β-ribo-hexoside; Adynerigenin 3'-methyl ether β-D-ribo-hexoside |
| EINECS | Contact for details |
Quality Control
Our 14-Hydroxy-3β-[[3-o-Methyl-4-(Methylamino)-2,4,6-Trideoxy-β-D-Ribo-Hexopyranosyl]Oxy]-5β,14β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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