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14-Hydroxy-3β-[[3-o-Methyl-4-(Methylamino)-2,4,6-Trideoxy-β-D-Ribo-Hexopyranosyl]Oxy]-5β,14β-Card-20(22)-Enolide CAS NO 22214-87-5


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CAS No.:22214-87-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

14-Hydroxy-3β-[[3-o-Methyl-4-(Methylamino)-2,4,6-Trideoxy-β-D-Ribo-Hexopyranosyl]Oxy]-5β,14β-Card-20(22)-Enolide is a high-purity, complex cardenolide glycoside of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate and reference standard for the synthesis and study of novel cardiac glycosides and related therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on cardiovascular drug discovery and development.

Application

  • Pharmaceutical Intermediate: A key building block in the synthetic pathway for novel cardiac glycoside drugs.
  • Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related active pharmaceutical ingredients (APIs).
  • Biochemical Research: Employed in studies investigating the mechanism of action of cardenolides on sodium-potassium ATPase pumps.
  • Preclinical Development: Serves as a starting material or comparator in the development of new therapeutic agents for heart failure and arrhythmias.
  • Academic Research: Utilized in university and institutional labs for pharmacological and structure-activity relationship (SAR) studies.

Basic Information

Product Name 14-Hydroxy-3β-[[3-o-Methyl-4-(Methylamino)-2,4,6-Trideoxy-β-D-Ribo-Hexopyranosyl]Oxy]-5β,14β-Card-20(22)-Enolide
CAS No. 22214-87-5
Molecular Formula C30H47NO8
Molecular Weight 549.70 g/mol
Synonyms 3'-O-Methyladynerigenin β-D-ribo-hexopyranoside; 3'-O-Methyladynerigenin β-D-ribo-hexoside; 14-Hydroxy-3β-[(3-O-methyl-4-methylamino-2,4,6-trideoxy-β-D-ribo-hexopyranosyl)oxy]-5β,14β-card-20(22)-enolide; 3'-O-Methyladynerigenin β-ribo-hexoside; Adynerigenin 3'-methyl ether β-D-ribo-hexoside
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Quality Control

Our 14-Hydroxy-3β-[[3-o-Methyl-4-(Methylamino)-2,4,6-Trideoxy-β-D-Ribo-Hexopyranosyl]Oxy]-5β,14β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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