Description

(S)-Enflurane is the single enantiomer of the halogenated ether anesthetic enflurane. This high-purity chiral compound is of significant value for advanced pharmaceutical research and development, particularly in the study of stereoselective pharmacology and metabolism. It is primarily required by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing novel anesthetic agents and conducting sophisticated biochemical studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Stereochemical Research: Critical for investigating the distinct biological activity, metabolic pathways, and receptor binding affinity of the (S)-enantiomer compared to the racemic mixture or the (R)-enantiomer.
• Metabolite Synthesis: Serves as a key chiral starting material or intermediate in the organic synthesis of potential drug metabolites for identification and toxicological evaluation.
• Analytical Method Development: Employed in chiral chromatography (HPLC, GC) to establish separation protocols and calibrate systems for enantiomeric purity analysis.
• Preclinical Studies: Utilized in in-vitro and in-vivo studies to understand the enantiomer-specific pharmacokinetics and pharmacodynamics of inhalation anesthetics.

Basic Information

Product Name	(S)-Enflurane
CAS No.	22194-21-4
Molecular Formula	C3H2ClF5O
Molecular Weight	184.49 g/mol
Synonyms	(S)-2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; (S)-2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane; (-)-Enflurane; L-Enflurane; (S)-Methylflurether; (S)-Ethrane; (S)-Alyrane
EINECS	244-834-8

Quality Control

Our (S)-Enflurane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by GC or HPLC, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) providing identity, purity, and enantiomeric excess data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, ideally at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Related Substances (GC)	≤ 1.0% (Total)
Water Content (KF)	≤ 0.1%
Residue on Evaporation	≤ 0.01%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.