Description

4-(4-Nitrophenyl)-6-Phenylpyrimidin-2(1H)-One is a high-purity, heterocyclic organic compound belonging to the pyrimidinone class, serving as a critical advanced intermediate for pharmaceutical and agrochemical research. Its value lies in its functionalized aromatic structure, which provides a versatile scaffold for synthesizing more complex molecules with targeted biological activity. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used as a precursor in the development of novel herbicides, fungicides, or plant growth regulators.
• Material Science: Serves as a monomer or functional component in the research of advanced polymers and organic electronic materials.
• Chemical Synthesis: Versatile intermediate for further functionalization (e.g., reduction of the nitro group, substitution reactions) to create libraries of derivatives for screening.
• Academic & Institutional Research: Used in universities and research institutes for studying heterocyclic chemistry, reaction mechanisms, and structure-activity relationships (SAR).

Basic Information

Product Name	4-(4-Nitrophenyl)-6-Phenylpyrimidin-2(1H)-One
CAS No.	22114-24-5
Molecular Formula	C₁₆H₁₁N₃O₃
Molecular Weight	293.28 g/mol
Synonyms	2(1H)-Pyrimidinone, 4-(4-nitrophenyl)-6-phenyl-; 4-(p-Nitrophenyl)-6-phenyl-2(1H)-pyrimidinone; 4-(4-Nitrophenyl)-6-phenyl-1H-pyrimidin-2-one; 6-Phenyl-4-(4-nitrophenyl)pyrimidin-2(1H)-one; 4-(4-Nitrophenyl)-6-phenyl-1,2-dihydropyrimidin-2-one; 4-(4-Nitrophenyl)-6-phenylpyrimidin-2-ol (tautomer); 22114-24-5; 4-(4-Nitrophenyl)-6-phenyl-2-hydroxypyrimidine
EINECS	Contact for details

Quality Control

Our 4-(4-Nitrophenyl)-6-Phenylpyrimidin-2(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.