Description

Glycyl-Hydroxyprolyl-Proline is a high-purity tripeptide derivative, widely recognized for its role in collagen metabolism and related biochemical pathways. This compound is valued for its consistent quality and stability, making it a critical component in advanced research and development. It is primarily utilized by the pharmaceutical, biotechnology, and cosmetic industries for applications in enzyme studies, formulation development, and as a reference standard.

Application

• Pharmaceutical Research: Used as a reference standard and substrate in enzyme inhibition studies, particularly for collagenase and related proteases.
• Biochemical Assays: Serves as a key intermediate or model compound in the study of collagen synthesis, degradation, and peptide metabolism.
• Cosmetic Science: Incorporated into advanced skincare formulations targeting collagen support and skin barrier function.
• Nutraceutical Development: Investigated for potential applications in dietary supplements focused on connective tissue health.
• Diagnostic Reagents: Employed in the development of diagnostic kits and assays for conditions related to collagen disorders.
• Academic & Industrial R&D: A fundamental building block for peptide synthesis and metabolic pathway research in laboratory settings.

Basic Information

Product Name	Glycyl-Hydroxyprolyl-Proline
CAS No.	22028-82-6
Molecular Formula	C15H23N3O6
Molecular Weight	341.36 g/mol
Synonyms	Gly-Hyp-Pro; GHP; Glycyl-L-hydroxyprolyl-L-proline; L-Glycyl-trans-4-hydroxy-L-prolyl-L-proline; H-Gly-Hyp-Pro-OH; Tripeptide GHP; Collagen Tripeptide; (2S)-1-[(2S)-2-[[(2S)-2-Aminoacetyl]amino]-5-hydroxy-1-oxopentan-2-yl]pyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Glycyl-Hydroxyprolyl-Proline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.