Description

H-Gly-Ala-Hyp-Oh is a synthetic tripeptide composed of glycine, alanine, and hydroxyproline. This compound is a crucial building block in peptide synthesis and biochemical research, offering high purity and reliable performance for advanced applications. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in collagen-related studies, peptide drug discovery, and the development of novel biomaterials.

Application

• Peptide Synthesis: A key intermediate for the solid-phase or solution-phase synthesis of longer, more complex collagen-like peptides and protein fragments.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, particularly those involving collagenases, peptidases, and other proteolytic enzymes.
• Pharmaceutical Development: Serves as a precursor in the research and development of therapeutic peptides targeting skin health, wound healing, and connective tissue disorders.
• Cosmeceutical Research: Investigated for its potential application in anti-aging and skin-rejuvenation formulations due to its structural similarity to natural collagen sequences.
• Biomaterial Science: Employed in the design and fabrication of synthetic extracellular matrices, hydrogels, and other scaffolds for tissue engineering.
• Analytical Standards: Used as a high-purity reference standard in HPLC, LC-MS, and other analytical methods for quality control and method validation.

Basic Information

Product Name	H-Gly-Ala-Hyp-Oh
CAS No.	22028-81-5
Molecular Formula	C10H17N3O5
Molecular Weight	259.26 g/mol
Synonyms	Glycyl-Alanyl-Hydroxyproline; Gly-Ala-Hyp; G-A-Hyp-OH; H-Gly-Ala-Hyp-OH; Tripeptide Gly-Ala-Hyp; (2S)-1-[(2S)-2-[(2-Aminoacetyl)amino]propanoyl]-4-hydroxypyrrolidine-2-carboxylic acid; Glycine-Alanine-Hydroxyproline; Collagen Tripeptide Fragment
EINECS	Contact for details

Quality Control

Our H-Gly-Ala-Hyp-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via mass spectrometry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.