Description

Acth (1-13) CAS NO 22006-64-0 is a synthetic peptide fragment of the adrenocorticotropic hormone (ACTH), representing its biologically active N-terminal sequence. This compound is a critical research tool for studying the structure-activity relationships of ACTH and its role in stimulating corticosteroid production. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on endocrinology, peptide chemistry, and therapeutic development.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of diagnostic agents and potential therapeutic compounds targeting adrenal function.
• Biochemical & Endocrinology Studies: Essential for in vitro and in vivo research to investigate the mechanism of ACTH receptor binding, steroidogenesis, and the hypothalamic-pituitary-adrenal (HPA) axis.
• Peptide Chemistry & Synthesis: Serves as a key building block or model compound for studying peptide synthesis methodologies, stability, and purification techniques.
• Diagnostic Kit Development: Employed in the formulation and calibration of immunoassay kits designed to measure ACTH levels or related biomarkers in clinical samples.
• Academic & Institutional Research: A fundamental reagent for graduate and post-doctoral studies in molecular biology, physiology, and peptide hormone action.
• Quality Control & Standardization: Acts as a certified reference material (CRM) for the quality assurance and validation of analytical methods in regulatory and manufacturing environments.

Basic Information

Product Name	Acth (1-13)
CAS No.	22006-64-0
Molecular Formula	C₇₅H₁₁₃N₂₁O₂₀S
Molecular Weight	1647.9 g/mol
Synonyms	ACTH (1-13); Adrenocorticotropic Hormone (1-13); α-MSH (1-13); Melanotropin (1-13); Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val; H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-OH; Corticotropin (1-13); Norleusactide
EINECS	Contact for details

Quality Control

Our Acth (1-13) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all specification parameters to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.