Description

Z-Phe-Ala-Oh is a protected dipeptide building block, widely recognized in the field of peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise stereochemistry. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for drug discovery, development of peptide-based therapeutics, and biochemical studies.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of novel therapeutic peptides.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research.
• Peptide Library Construction: Enables the creation of diverse peptide libraries for high-throughput screening in drug discovery.
• API Development: Serves as a critical intermediate in the development and scale-up of Active Pharmaceutical Ingredients (APIs).
• Academic & R&D: Fundamental reagent for synthetic organic chemistry and peptide methodology research in laboratories.

Basic Information

Product Name	Z-Phe-Ala-Oh
CAS No.	21881-18-5
Molecular Formula	C₂₀H₂₂N₂O₅
Molecular Weight	370.40 g/mol
Synonyms	N-Carbobenzoxy-L-phenylalanyl-L-alanine; Z-L-Phenylalanyl-L-alanine; Z-Phe-Ala; Cbz-Phe-Ala-OH; N-(Benzyloxycarbonyl)-L-phenylalanyl-L-alanine; Nα-Cbz-L-Phenylalanyl-L-alanine; (2S)-2-[[(2S)-2-(benzyloxycarbonylamino)-3-phenylpropanoyl]amino]propanoic acid; CBZ-Phenylalanine-Alanine
EINECS	Contact for details

Quality Control

Our Z-Phe-Ala-Oh is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	-15.0° to -20.0° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.