Description

4-Amino-3-Hydroxyphenylalanine Dihydrochloride is a specialized aromatic amino acid derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical chiral building block and precursor for the synthesis of complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic agents, and biochemical probes. Its unique structure, incorporating both amino and hydroxyl functional groups on the phenylalanine backbone, makes it a valuable intermediate for targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for neurological and metabolic disorders.
• Biochemical Research: Used as a precursor or standard in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Peptide Synthesis: Serves as a protected or modified amino acid residue in the solid-phase and solution-phase synthesis of specialized peptides and peptidomimetics.
• Diagnostic Agent Development: Employed in the design and synthesis of contrast agents or molecular probes for imaging techniques like PET or MRI.
• Enzyme Substrate/Analog: Acts as a substrate or inhibitor in studies of enzymes such as tyrosine hydroxylase, aromatic L-amino acid decarboxylase, and other related enzymes.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	4-Amino-3-Hydroxyphenylalanine Dihydrochloride
CAS No.	21819-90-9
Molecular Formula	C9H14Cl2N2O3
Molecular Weight	269.12 g/mol
Synonyms	3-Hydroxy-4-aminophenylalanine dihydrochloride; L-4-Amino-3-hydroxyphenylalanine dihydrochloride; 4-Amino-3-hydroxy-DL-phenylalanine dihydrochloride; 2-Amino-3-(4-amino-3-hydroxyphenyl)propanoic acid dihydrochloride; α-Amino-4-amino-3-hydroxybenzenepropanoic acid dihydrochloride; AHP Dihydrochloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Hydroxyphenylalanine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and residual solvent testing, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.