Description

Hydroxythreonine is a non-proteinogenic amino acid derivative of threonine, characterized by an additional hydroxyl group on its side chain. This structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the life sciences sector for developing novel compounds and studying biochemical pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for antibiotics and enzyme inhibitors.
• Biochemical Research: Used as a standard or reagent in metabolic pathway studies, enzyme-substrate interaction assays, and proteomics research.
• Peptide Synthesis: Incorporated into custom peptides to introduce specific hydroxyl functionality, altering solubility, binding properties, or stability.
• Nutritional Science Studies: Employed in research investigating amino acid metabolism, nutritional supplements, and specialized dietary formulations.
• Cosmetic Ingredient Development: Explored for use in high-end skincare formulations for its potential moisturizing and skin-conditioning properties.
• Agrochemical Research: Investigated as a precursor for synthesizing novel, biodegradable plant growth regulators or herbicides.

Basic Information

Product Name	Hydroxythreonine
CAS No.	21768-45-6
Molecular Formula	C4H9NO4
Molecular Weight	135.12 g/mol
Synonyms	2-Amino-3,4-dihydroxybutyric Acid; three-3,4-Dihydroxybutyric Acid; (2S,3R)-2-Amino-3,4-dihydroxybutanoic Acid; β-Hydroxythreonine; L-threo-3,4-Dihydroxybutyric Acid; 3,4-Dihydroxy-L-threonine; Amino Dihydroxybutyric Acid
EINECS	Contact for details

Quality Control

Our Hydroxythreonine is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure high chemical purity and identity, with testing typically including identification (IR), assay (HPLC), and control of specific impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.